منابع مشابه
Apoptotic cells let down their guard
Unfolding chromatin nets Spiderman doesn’t have anything on neutrophils, which snag microscopic bad guys with webs of chromatin. Wang et al. show that by unfurling chromatin, a histone-modifying protein helps the defensive cells set their traps. During an infection or infl ammation, dying neutrophils spill their DNA to form pathogentrapping NETs (neutrophil extracellular traps). This gooey mate...
متن کاملDelayed Lead Perforation: Can We Ever Let the Guard Down?
Lead perforation is a major complication of cardiac rhythm management devices (CRMD), occurring in about 1%. While most lead perforations occur early, numerous instances of delayed lead perforation (occurring >30 days after implantation) have been reported in the last few years. Only about 40 such cases have been published, with the majority occurring <1 year after implantation. Herein, we desc...
متن کاملMicroRNA let-7 establishes expression of beta2-adrenergic receptors and dynamically down-regulates agonist-promoted down-regulation.
Although β(2)-adrenergic receptors (β(2)AR) are expressed on most cell types, mechanisms that establish expression levels and regulate expression by chronic agonist remain unclear. The 3' UTR of ADRB2 has a conserved 8-nucleotide seed region that we hypothesized is targeted by the let-7 family of miRNAs leading to translational repression. In luciferase assays with transfected cells, luc-β(2)WT...
متن کاملTreatment of the pancreatic stump after DCP.
OBJECTIVE With improvement in methods, mortality after duodeno-cefalo pancreatectomy (DCP) has decreased to 5% even if complication rate is still high (30-50%). The pancreatic fistula still occurs in 25-50% of cases. Various methods of treating pancreatic stump have been proposed aimed to improve this rate. PATIENTS AND METHODS The AA, surgeons of suburban hospital, have performed in five yea...
متن کاملDepression; Let\'s talk
April 7 is known as “World Health Day” and one of the main responsibilities of World Health Organization is to improve the knowledge of the world population in order to prevent various diseases(1). This organization selects an illness or a disorder in terms of a unique slogan in order to plan for educational, prevention, curative and re-strengthening the operation of countries aroun...
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ژورنال
عنوان ژورنال: British Dental Journal
سال: 2009
ISSN: 0007-0610,1476-5373
DOI: 10.1038/sj.bdj.2009.360